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HomeShobha –  Products

S.NO API CAS NO THERAPEUTIC USE pharmacopoeia Docs Available
1 Ezetimibe 163222-33-1 Anti-hyperlipidaemic IP/USP DMF, WHO GMP, WC
2 Dorzolamide Hydrochloride 130693-82-2 Glaucoma IP/EP/USP CEP, DMF, WC, WHO GMP
3 Bilastine 202189-78-4 Anti-Histamine IH/IP DMF, WHO GMP, WC
4 Rivaroxaban 366789-02-8 Anticoagulant IP/EP/USP Under Development
5 Suvorexant 1030377-33-3 Insomnia IH DMF, WHO GMP, WC
6 Bempedoic Acid 738606-46-7 Lipid Lowering Agent IH Under Development
S.NO INTERMEDIATE NAME CAS NO Code STATUS
EZETIMIBE
1 (S)-(+)-4-Phenyl-2-oxazolidinone 99395-88-7 SPOZ Reagent & commercialized
2 (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone 189028-93-1 EZE-2 Intermediate & commercialized
3 4-[[(4-Fluorophenyl) imino]methyl]-phenol 3382-63-6 EZE-S2 Key starting material & commercialized
4 (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one 1185883-40-2 EZE-5 Intermediate & commercialized
5 (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl) oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one 272778-12-8 EZT-4 Intermediate & commercialized
DORZOLAMIDE HYDROCHLORIDE
6 (3S)-3-(2-Thienylthio) butanoic acid 133359-80-5 DOR-H1 Advanced Key starting material & commercialized (100% Indigenous)
7 (6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b] thiopyran-4-one 148719-91-9 DOR-2 Key starting material & commercialized (100% Indigenous)
8 (4R,6S)-5,6-Dihydro-4-hydroxy-6-methylthieno [2,3-b] thiopyran-7,7-dioxide 147128-77-6 DOZ-S1 Key starting material & commercialized (100% Indigenous)
9 N-[(4S,6S)-6-Methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b] thiopyran-4-yl] acetamide 147086-83-7 DOZ-1 Advanced Intermediate & commercialized (100% Indigenous)
10 N-[(4S,6S)-2-(Aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno[2,3-b] thiopyran-4-yl] acetamide 147200-03-1 DOZ-4 Advanced Intermediate & commercialized (100% Indigenous)
BILASTINE
11 Methyl-2-(4-(2-chloroethyl)phenyl-2-methylpropanoate 1181267-33-3 BIL-S1 Key starting material & commercialized (100% Indigenous)
12 1-(2-Ethoxyethyl)2-(piperidin-4-yl)1H-benzo[d]imidazole hydrochloride 1841081-72-8 BIL-S2 Key starting material & commercialized (100% Indigenous)
13 Methyl2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl) piperidin-1-yl) ethyl) phenyl)-2-methylpropanoate (Bilastine Ester) 1181267-38-8 BIL-Ester Advanced Intermediate & commercialized (100% Indigenous)
RIVAROXABAN
14 4-(4-Aminophenyl) morpholin-3-one 438056-69-0 RIV-S1 Key starting material & commercialized (100% Indigenous)
15 (S)-(+)-N-(2,3-Epoxypropyl)phthalimide 161596-47-0 RIV-S2 Key starting material & commercialized (100% Indigenous)
16 5-Chlorothiophene-2-carboxylic acid 24065-33-6 RIV-S3 Key starting material & commercialized (100% Indigenous)
17 2-[(2R)-2-Hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione 446292-07-5 RIV-1 Advanced Intermediate & Commercialized (100% Indigenous)
18 2-{(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl}-1H-isoindole-1,3(2H)-dione 446292-08-6 RIV-2 Advanced Intermediate & Commercialized (100% Indigenous)
19 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one hydrochloride 898543-06-1 RIV-3 Advanced Intermediate & Commercialized (100% Indigenous)
SUVOREXANT
20 5-chloro-1,3-benzoxazole-2-thiol 22876-19-3 DBX-I Advanced Intermediate & Commercialized (100% Indigenous)
21 (R)-Benzyl-5-methyl-1,4-diazepane-1-carboxylate 1001401-60-0 SUV-S1 Advanced Intermediate (100% Indigenous)
22 5-Methyl-2-(2H-1,2,3-triazole-2-yl) benzoic acid 956317-36-5 SUV-S2 Advanced Intermediate (100% Indigenous)
23 2,5-Dichloro-1,3-Benzoxazole 3621-81-6 SUV-S3 Advanced Intermediate & Commercialized (100% Indigenous)
24 Benzyl (5R)-5-methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepane-1-carboxylate 1030377-31-1 SUV-1 Commercialized (100% Indigenous)
25 (7R)-7-Methyl-1-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepane 1030377-32-2 SUV-2 Advanced Intermediate & Commercialized (100% Indigenous)
BOSENTAN
26 Dimethyl-2-chloromalonate 28868-76-0 2-CDM Key starting material & commercialized (100% Indigenous)
CHIRAL RESOLVING AGENT
27 R-(-)-N-(3,5-Dinitrobenzoyl)-α-Phenylglycine 74927-72-3 DPG Advanced Intermediate & Commercialized (100% Indigenous)
ALOGLIPTIN/LINGLIPTIN/TRELAGLIPTIN
28 (R)-3-Aminopiperidine Dihydrochloride 334618-23-4 APD Advanced Intermediate & Commercialized (100% Indigenous)
CINACALCET HYDROCHLORIDE
29 1-(1-Naphthelen-1-yl)ethaneamine 3886-70-2 NEA Key starting material for cinacalcet HCl & commercialized (100% Indigenous)
BEMPEDOIC ACID
30 Ethyl 7-bromo-2,2-dimethylheptanoate 123469-92-1 BEM-S1 Advanced Intermediate for Bempedoic Acid & Commercialized (100% Indigenous)
31 Diethyl 2,2,14,14-tetramethyl-8-oxopentadecanedioate 738606-43-4 BEM-2 Advanced Intermediate for Bempedoic Acid & Commercialized (100% Indigenous)
32 2,2,14,14-tetramethyl-8-oxopentadecanedioic acid 413624-71-2 BEM-3 Advanced Intermediate for Bempedoic Acid & Commercialized (100% Indigenous)

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Shobha Life Sciences is a Hyderabad based preclinical contract research organization providing facilities for various preclinical experiments like stability studies, pharmacokinetic, pharmacodynamic, toxicological and efficacy studies.

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